STRUCTURAL, THEORETICAL INVESTIGATIONS AND BIOLOGICAL EVALUATION OF CU(II), NI(II) AND CO(II) COMPLEXES OF MERCAPTO-PYRIMIDINE SCHIFF BASES

Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/2086

Full metadata record

DC Field	Value	Language
dc.contributor.author	JoneKirubavathy S	-
dc.contributor.author	Chitra S	-
dc.date.accessioned	2020-10-06T05:25:13Z	-
dc.date.available	2020-10-06T05:25:13Z	-
dc.date.issued	2017	-
dc.identifier.uri	https://doi.org/10.1016/j.molstruc.2017.07.019	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/2086	-
dc.description.abstract	A new series of transition metal complexes of mercapto pyrimidine Schiff base complexes has been studied and characterized using various spectral techniques like single crystal XRD, FT-IR, electronic, EDX and TGA. The molecular properties of the ligand and the complexes have been derived from HOMOLUMO calculations using Gaussian software. The biological evaluation of the ligands and the complexes has been studied and compared. The DNA binding studies of the complexes has been carried out and the binding constants are in the order of 104 M1 . The DNA cleavage activity of the complexes proves the mechanism of cleavage is through non-hydrolytic pathway	en_US
dc.language.iso	en	en_US
dc.publisher	Journal of Molecular Structure, Elsevier	en_US
dc.subject	Mercaptoschiff base complexes	en_US
dc.subject	DNA cleavage	en_US
dc.subject	HOMO-LUMO	en_US
dc.subject	DNA binding	en_US
dc.subject	Biological activity	en_US
dc.title	STRUCTURAL, THEORETICAL INVESTIGATIONS AND BIOLOGICAL EVALUATION OF CU(II), NI(II) AND CO(II) COMPLEXES OF MERCAPTO-PYRIMIDINE SCHIFF BASES	en_US
dc.type	Article	en_US
Appears in Collections:	International Journals

Files in This Item:

File	Description	Size	Format
STRUCTURAL, THEORETICAL INVESTIGATIONS AND BIOLOGICAL EVALUATION OF CU(II), NI(II) AND CO(II) COMPLEXES OF MERCAPTO-PYRIMIDINE SCHIFF BASES.docx		10.17 kB	Microsoft Word XML	View/Open