ANDROGRAPHIS PANICULATE MEDIATED BIOSYNTHESIS OF SILVER NANOPARTICLES AND ITS ANTIBACTERIAL ACTIVITY AGAINST HUMAN PATHOGENS

Abstract

Development of reliable biological route to synthesis nanoparticles is essential for their potential applications in diverse fields, especially in antimicrobial activity against human pathogens. The present work is also evidencefor the plant mediated synthesis of silver nanoparticles showing a greater consequence against microbes.This study deals with the synthesis of silver nanoparticles by treating silver nitrate with aqueous extract of Andrographispaniculata at room temperature. The effect of the Andrographis paniculataaqueous extract on the formation of silver nanoparticles was characterized by UVvisible spectroscopy (UV-Vis), X-ray Diffraction Spectrum (XRD), Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDX). The UV spectra results show a strong resonance centre and surface of silver nanoparticles (AgNPs) at 443 nm. XRD and SEM studies revealed that the synthesized AgNPs shows spherical shape.