Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/4262
Full metadata record
DC FieldValueLanguage
dc.contributor.authorJone Kirubavathy, S-
dc.contributor.authorVelmurugan, R-
dc.contributor.authorKarvembu, R-
dc.contributor.authorBhuvanesh, N S P-
dc.contributor.authorEnoch, I V M V-
dc.contributor.authorMosae Selvakumar, P-
dc.contributor.authorChitra, S-
dc.date.accessioned2023-11-18T03:59:51Z-
dc.date.available2023-11-18T03:59:51Z-
dc.date.issued2016-11-
dc.identifier.urihttps://nopr.niscpr.res.in/bitstream/123456789/37054/1/IJCA%2055A%2811%29%201297-1304.pdf-
dc.description.abstractCobalt(II) complex of 2-amino-6-methylbenzothiazole has been synthesized and characterized by various physicochemical methods. The ligand 2-amino-6-methylbenzothiazole acts as monodentate, neutral ligand with N as the donor site. The molecular structure of the title complex has been determined by single crystal X-ray diffraction studies. The Co(II) complex shows significant antioxidant activity against DPPH radical. The complex shows cytotoxicity with a IC50 value of 14.12 µM against MCF-7 cell line. In addition, the complex shows good antimicrobial and anti-tuberculosis activities against various microbes and mycobacterium tuberculosis respectively. DNA binding of the title complex has been investigated by absorption spectroscopic technique, which reveals that the complex acts as minor groove binder. These results have been validated by molecular docking studiesen_US
dc.language.isoen_USen_US
dc.publisherIndian Journal of Chemistryen_US
dc.subjectCo-ordination chemistryen_US
dc.subjectCobalten_US
dc.subjectBenzothiazoleen_US
dc.subjectMagnetic propertiesen_US
dc.subjectAntituberculosis activityen_US
dc.subjectMolecular dockingen_US
dc.titleCO(II) COMPLEX OF 2-AMINO-6-METHYLBENZOTHIAZOLE: SYNTHESIS, STRUCTURE AND BIOLOGICAL EVALUATIONen_US
dc.typeArticleen_US
Appears in Collections:2.Article (31)



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.