SYNTHESIS, STRUCTURAL, CHEMOSENSOR AND MOLECULAR DOCKING STUDIES OF NOVEL IMINO TRIPHENOL FROM AMMONIUM ACETATE AND SALICYLALDEHYDE

Abstract

Novel Tris-iminophenol namely, 2-((z-((e)-2-hydroxybenzylideneamino) (2-hydroxyphenyl) methyl-imino) methyl) phenol was synthesized by reacting ammonium acetate and salicylaldehyde at 0 °C and characterized using various spectral techniques like singe crystal XRD, FT-IR, UV–Visible spectroscopy. Single crystal XRD shows the system to be monoclinic space group C12/c1 with the unit cell dimensions a = 16.965(3) Å, b = 12.2652(19) Å, c = 18.092(3) Å and β=112.455(2) Å. The molecular docking studies of the synthesized compound prove to have good ADMET properties and the antimicrobial studies shows its excellent activity against E. Coli. The electronic absorption and fluorescence response studied shows that the phenolic compound has great affinity towards Fe2+ ion.