A SYSTEMATIC REVIEW ON BISPHENOLS – SOURCES, HEALTH IMPACTS, AND ANALYTICAL DETERMINATION OF BISPHENOL A IN AQUEOUS SAMPLES

Abstract

Bisphenol A and its structural analogs are used by industrial processes for the manufacture of plastics, and medical and electronic devices. When these products are disposed of, they tend to leach out causing pollution and impacting human health. Thus, many studies are focused on detecting the presence of Bisphenols in environmental matrices, especially in water and food, as it is a major route of human exposure. Advancements have been made in the preparation and detection of samples using different analytical techniques. The most widely used techniques for bisphenol detection are liquid chromatography and gas chromatography coupled with mass spectroscopy. The progress made for ultra-trace detection of Bisphenols via the development of efficient sample extraction techniques and the benefits of each technique are highlighted. The recent advances in detection techniques using colorimetric and Raman spectroscopy are reviewed with an emphasis on the use of portable onsite techniques compared to conventional labor-intensive and time-consuming techniques. An overview of all the approaches to determining Bisphenols in environmental and food samples is discussed in detail to provide insight into the progress made in this field.