UNVEILING THE DUAL FUNCTIONALITY OF DIMERIC CU(I)/(II) CRYSTAL AS LUMINESCENCE AND ELECTROCHEMICAL PROBE FOR ZN2+ AND GLUCOSE DETECTION—STRUCTURAL, SENSING AND MOLECULAR DOCKING STUDIES

Abstract

A new crystalline dinuclear Cu(I)/(II) complex (E.F: C32H28Cu2N6O14) (1) of terephthalic acid (TERE) and 1, 10-Phenathroline (PHEN) was synthesized under one-pot approach. Structure identification of the complex was carried out using the single crystal XRD technique, which revealed the penta coordination nature of Cu(I)/(II) in a square pyramidal environment. Further, the structural data was supported by employing other spectroscopic studies (UV, ESR, FT-IR). In addition, the thermal stability and morphology of the complex were elucidated using TGA and SEM-EDAX analysis. Photoluminescence experiments revealed the capability of 1 to act as a “turn-off” sensor towards Zn2+ sensing. This luminescence quenching of 1 exhibited a threefold quenching in intensity by achieving a static quenching process corresponding to a limit of detection (LOD) of 3.7 μM. Further, considering the electroactive nature of Cu(I)/(II) complex, the cyclic voltammetric experiments were performed to study its competence to act as a modifier of GCE for the detection of glucose and its excellent potency to act as an effective electroactive material in the detection of glucose solutions. Also, molecular docking of 1 with human bovine serum (HSA) and bovine serum albumin (BSA) was investigated to prove their ability to act as pharmacological agents.